When cancer starts to spread to other parts of the body this a process called metastasis. It becomes much more difficult to treat. New research, published in the journal Cell Reports and led by the University of Sydney in Australia identifies "bad" cholesterol helps in metastasis of cancer. Cancer happens when normal cells grow out of control and multiply to form lumps called tumors. If untreated, cancer cells can escape their primary tumors, travel to other parts of the body and grow into secondary cancers or metastases(note: Metastasis & metastases both are different). Metastases are the major cause of death from cancer.
Researchers have discovered that integrins can move from the surface of cells to the inside, and that cholesterol, one of the major lipids in the body, is needed to keep integrins on the surface of cancer cells. But the underlying mechanisms, until now is still under-research.
By manipulate and lower 'bad' cholesterol could significantly help to reduce the ability of cancer cells to spread.
-Written by Devesh Chaudhari
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